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Commonly in liquid form and available in various chemical compositions, solvents are substances that dissolve solutes to form solutions. The amount and type of solute that a solvent can dissolve is dependent upon temperature and polarity.
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Malonyl CoA lithium is an inhibitor of carnitine palmitoyl transferase 1 (CPT1). High Malonyl CoA lithium concentrations suppress fatty acid oxidation, while low Malonyl CoA lithium concentrations are permissive for fat oxidation.
Inhibitor of carnitine palmitoyl transferase 1 (CPT1).
High concentrations suppress fatty acid oxidation.
Low concentrations are permissive for fat oxidation.
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Sphingosine-1-phosphate (S1P) is an agonist of S1P1-5 receptors and a ligand of GPR3, GPR6 and GPR12. Sphingosine-1-phosphate is an intracellular second messenger and mobilizes Ca2+ as an extracellular ligand for G protein-coupled receptors. Sphingosine-1-phosphate is an important lipid mediator generated from Sphingomyelin (HY-113498) or other membrane phospholipids.
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Pipecolic acid-d9 is the deuterium labeled Pipecolic acid Pipecolic acid is a metabolite of lysine and an important precursor for many useful microbial secondary metabolites Pipecolic acid slows ferroptosis in diabetic retinopathy by inhibiting the YAP-GPX4 signaling pathway In addition Pipecolic acid can be used as a diagnostic marker for pyridoxine-dependent epilepsy[1][2][3]
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Sitagliptin-d4 phosphate is the deuterium-labeled isotopologue of sitagliptin phosphate provided as an analytical reference standard. It is used as a labeled internal standard in LC-MS and other bioanalytical assays to enable accurate quantification of sitagliptin and to support studies of DPP-4 inhibition.
Deuterium-labeled internal standard for accurate quantification.
High purity (≈99.5%) suitable for analytical use.
Provides clear isotopic distinction in mass spectrometry assays.
Stable when stored at 4°C; in solvent store at -80°C (6 months) or -20°C (1 month).
Supplied in small pack sizes convenient for laboratory use.
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Methyl yellow-d5 is the deuterium-labeled analogue of methyl yellow (Solvent Yellow 2), provided as a stable isotope standard for analytical and tracer applications. It is supplied as a high-purity solid reference material suitable for use as an internal standard in mass spectrometry and method development.
High isotopic purity suitable for internal standard use.
Compatible with mass spectrometry and liquid chromatography methods.
Supplied as a stable, solid isotope-labeled standard for analytical workflows.
Available in small milligram pack sizes for reference and validation.
Documentation available includes certificate of analysis and safety data sheet for traceability.
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2-Naphthol-d7 is the deuterium labeled 2-Naphthol[1] 2-Naphthol is a metabolite of naphthalene catalyzed by cytochrome P450 (CYP) isozymes (CYP 1A1 CYP 1A2 CYP 2A1 CYP 2E1 and CYP 2F2)[2]
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Repaglinide-d5 is a deuterium-labeled analogue of repaglinide supplied for research and analytical use. It is intended as an internal standard or tracer for quantitative analysis and method development, and is used to support studies of repaglinide pharmacology and metabolism.
Deuterium-labeled internal standard for analytical quantification.
Suitable for LC-MS, GC-MS, and NMR applications.
High purity to support accurate analytical results.
Provided as a small research-grade sample for method validation and tracer studies.
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Ac-Exatecan-d5 is the deuterium-labeled version of Ac-Exatecan. This compound is intended for research use only and is not sold to patients.
Can be used as a tracer and as an internal standard for quantitative analysis via NMR, GC-MS, or LC-MS.
Deuterium substitution in drug molecules is largely used as a tracer for quantitation during drug development and has the potential to influence the pharmacokinetic and metabolic profiles of drugs.
Molecular weight: 482.52.
Appearance: Solid, light yellow to yellow.
Ships at room temperature in the continental US (may vary elsewhere). Store at 4°C, sealed, away from moisture. In solvent, store at -80°C for 6 months or -20°C for 1 month (sealed, away from moisture).
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